A case of Vogt-Koyanagi-Harada disease manifesting multiple white dots with ultimate visual recovery

Tomoko Shiba, Toshiaki Abe, Madoka Yoshida, Motohiko Seimiya, Ryosuke Wakusawa, Yuko Wada, Makoto Tamai

Research output: Contribution to journalArticlepeer-review

Abstract

Purpose: To report a case of Vogt-Koyanagi-Harada (VKH) disease who manifested multiple white dots during the course of recovery with ultimate visual recovery. Case: A 30-year-old female was referred to us for headache, metamorphopsia, and symptoms simulating common cold. Corrected visual acuity was 0.15 right and 0.07 left. Both eyes showed serous retinal detachment. She also showed sensorineural deafness and pleocytosis in the spinal fluid. These findings lead to the diagnosis of VKH disease. Nine days after start of megadosis of prednisolone, retinal detachment disappeared followed by appearance of white dots. By fluorescein angiography, the dots showed hypofluorescence in the initial phase and hyperfluorescence in the late phase. The dots later turned into gray ones. Visual acuity recovered to 0.9 right and 1.0 left. Alopecia appeared later. Conclusion: White dots in the present case of VKH disease appeared similar to those in serpiginous choroiditis or acute posterior multifocal placoid pigmentopathy. There is a possibility that these three fundus diseases may have causative mechanisms in common.

Original languageEnglish
Pages (from-to)1563-1571
Number of pages9
JournalJapanese Journal of Clinical Ophthalmology
Volume67
Issue number9
Publication statusPublished - 2013 Sep 24

ASJC Scopus subject areas

  • Ophthalmology

Fingerprint Dive into the research topics of 'A case of Vogt-Koyanagi-Harada disease manifesting multiple white dots with ultimate visual recovery'. Together they form a unique fingerprint.

Cite this