A Case of Undifferentiated Carcinoma of the Sigmoid Colon That Responded to Paclitaxel and Carboplatin Chemotherapy

Shingo Toyama, Katsuyoshi Kudoh, Shinobu Ohnuma, Satoko Sato, Naoki Tanaka, Takeshi Aoki, Hirofumi Imoto, Hideaki Karasawa, Kazuhiro Watanabe, Munenori Nagao, Tomoya Abe, Hiroaki Musha, Fuyuhiko Motoi, Takeshi Naitoh, Michiaki Unno

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

We report a case of a 72-year-old woman who was initially diagnosed with ovarian cancer with peritoneal carcinomatosis. Systemic chemotherapy consisting of paclitaxel and carboplatin(TC)was administered. Although a partial response(PR)was achieved after the 4 courses of TC, this regimen was discontinued due to severe adverse events. Ten months after discontinuation of TC, because abdominal CT and colonoscopy showed an intra-tumoral abscess caused by invasion of the tumor to the sigmoid colon, abdominal total hysterectomy, bilateral salpingo-oophorectomy, and a Hartmann's operation were performed to control the disease symptoms. Pathological examination revealed that the tumor was an undifferentiated carcinoma of the sigmoid colon. This case report suggests that the TC regimen may be effective for treating undifferentiated carcinoma of the colon.

Original languageEnglish
Pages (from-to)2295-2297
Number of pages3
JournalGan to kagaku ryoho. Cancer & chemotherapy
Volume43
Issue number12
Publication statusPublished - 2016 Nov 1

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

Fingerprint Dive into the research topics of 'A Case of Undifferentiated Carcinoma of the Sigmoid Colon That Responded to Paclitaxel and Carboplatin Chemotherapy'. Together they form a unique fingerprint.

Cite this