A Case of Successful Simultaneous Pancreas-Kidney Transplantation Using the Injured Pancreas Graft

Shigehito Miyagi, Kenji Shimizu, K. Miyazawa, Wataru Nakanishi, Y. Hara, Kazuaki Tokodai, Chikashi Nakanishi, S. Satomi, Masafumi Goto, Michiaki Unno, Takashi Kamei

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1 Citation (Scopus)

Abstract

Objective Graft injuries sometimes occur and may cause complications such as the leakage of pancreatic secretions, which is often lethal. We report our experience of a case of successful simultaneous pancreas-kidney transplantation using injured pancreas graft. Patients and methods The recipient was a 57-year-old woman with type 1 diabetes mellitus, and the donor was a 30-year-old man with a brain injury. In the donation, the pancreas parenchyma, splenic artery, and gastroduodenal artery were injured iatrogenically. We therefore reconstructed these arteries using vessel grafts and then performed simultaneous pancreas-kidney transplantation. Results Five days after transplantation, we noted a high titer of amylase in the ascites; therefore, we performed an urgent laparotomy. The origin of the amylase was the injured pancreatic parenchyma, and continued washing and drainage were carried out. We reconstructed the duodenojejunostomy using the Roux-en-Y technique to separate the passage of food from the pancreas graft to prevent injury to other organs due to exposure to pancreatic secretions. Thereafter, we inserted a decompression tube into the anastomosis thorough the blind end of the jejunum. Finally, we inserted 3 drainage tubes for lavage. Following this procedure, the patient recovered gradually and no longer required hemodialysis and insulin therapy. She was discharged from our hospital 56 days after transplantation. Conclusion The restoration of the injured graft was possible by management of pancreatic secretions and use of the donor's vessel grafts. Shortage of donors is a problem throughout the world; thus, it is important to use injured grafts for transplantation if possible.

Original languageEnglish
Pages (from-to)2315-2317
Number of pages3
JournalTransplantation Proceedings
Volume49
Issue number10
DOIs
Publication statusPublished - 2017 Dec 1

ASJC Scopus subject areas

  • Surgery
  • Transplantation

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