A case of stage IV gastric cancer with multiple liver metastases surviving for more than 4 years by treatment with chemotherapies without surgery

Toshinori Ando, Yoshiro Suzuki, Shinichi Kanno, Eishi Miyashita, Naoki Tanaka, Fumie Ikezawa, Chikashi Shibata, Iwao Sasaki, Takashi Yoshioka

Research output: Contribution to journalArticlepeer-review

Abstract

A 75-year-old male who with type 3 gastric cardia cancer with multiple liver metastases was initially treated with S-1 in July of 2005. After 4 courses of the treatment, the liver metastases became undetectable on abdominal CT scan, with reduction in size of the primary tumor of the stomach. After 7 months of S-1 treatment, however, the progression of the primary lesion was endoscopically detected, and irinotecan was administered, demonstrating primary tumor regression. When re-growth of the primary tumor was observed, 3 courses of paclitaxel treatment showed little effect and was replaced by docetaxel treatment for 5 months, which had a grade 3 adverse effect. The next 10 courses of 5-FU combined with methotrexate were applied for one year until the primary tumor showed enlargement. Then 12 courses of CDDP with S-1 were administered until now, and the size of the primary carcinoma is under control. The patient is being followed on an outpatient basis without any surgical treatment, while the liver metastases have not relapsed on abdominal imaging.

Original languageEnglish
Pages (from-to)891-894
Number of pages4
JournalJapanese Journal of Cancer and Chemotherapy
Volume37
Issue number5
Publication statusPublished - 2010 May

Keywords

  • S-1
  • Stage IV gastric cancer

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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