A case of polyarteritis nodosa limited to both calves with a low titer of MPO-ANCA

K. Iwamasa; H. Komori; Y. Niiya; H. Hasegawa; I. Sakai; S. Fujita; M. Yoshida; M. Nose

A case of polyarteritis nodosa limited to both calves with a low titer of MPO-ANCA

K. Iwamasa, H. Komori, Y. Niiya, H. Hasegawa, I. Sakai, S. Fujita, M. Yoshida, M. Nose

MED - Medical Sciences

Research output: Contribution to journal › Article › peer-review

6 Citations (Scopus)

Abstract

A-57-year-old woman had suffered from high fever, general malaise, and loss of weight (6 kg) since January, 2000. She was admitted to our hospital in May, 2000, because of gait disturbance following to swelling of bilateral calves with severe pain beside the above symptoms. Laboratory data showed leukocytosis (WBC 10,000/ μ1), high ESR (98 mm/hr), positive CRP (3.43mg/dl), positive ANA (x160), high titer of RA (266 IU/1), and a low titer of MPO-ANCA (18 EU). T 2-weighted magnetic resonance image (MRI) showed intensity area of the M. gastrocnemius. Skin biopsy specimens of the right leg demonstrated necrotizing arteritis of small-sized arteries. These findings supported the diagnosis of limited type of polyarteritis nodosa (PN). In this report, we demonstrate a rare case of PN limited to both calves with characteristic MRI findings and a low titer of MPO-ANCA.

Original language	English
Pages (from-to)	875-879
Number of pages	5
Journal	Ryumachi
Volume	41
Issue number	5
Publication status	Published - 2001 Dec 17

Keywords

Calf pain
Magnetic resonance images (MRI)
Microscopic polyangiitis
Myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA)
Polyarteritis nodosa

ASJC Scopus subject areas

Rheumatology

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title = "A case of polyarteritis nodosa limited to both calves with a low titer of MPO-ANCA",

abstract = "A-57-year-old woman had suffered from high fever, general malaise, and loss of weight (6 kg) since January, 2000. She was admitted to our hospital in May, 2000, because of gait disturbance following to swelling of bilateral calves with severe pain beside the above symptoms. Laboratory data showed leukocytosis (WBC 10,000/ μ1), high ESR (98 mm/hr), positive CRP (3.43mg/dl), positive ANA (x160), high titer of RA (266 IU/1), and a low titer of MPO-ANCA (18 EU). T 2-weighted magnetic resonance image (MRI) showed intensity area of the M. gastrocnemius. Skin biopsy specimens of the right leg demonstrated necrotizing arteritis of small-sized arteries. These findings supported the diagnosis of limited type of polyarteritis nodosa (PN). In this report, we demonstrate a rare case of PN limited to both calves with characteristic MRI findings and a low titer of MPO-ANCA.",

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author = "K. Iwamasa and H. Komori and Y. Niiya and H. Hasegawa and I. Sakai and S. Fujita and M. Yoshida and M. Nose",

year = "2001",

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AU - Iwamasa, K.

AU - Komori, H.

AU - Niiya, Y.

AU - Hasegawa, H.

AU - Sakai, I.

AU - Fujita, S.

AU - Yoshida, M.

AU - Nose, M.

PY - 2001/12/17

Y1 - 2001/12/17

N2 - A-57-year-old woman had suffered from high fever, general malaise, and loss of weight (6 kg) since January, 2000. She was admitted to our hospital in May, 2000, because of gait disturbance following to swelling of bilateral calves with severe pain beside the above symptoms. Laboratory data showed leukocytosis (WBC 10,000/ μ1), high ESR (98 mm/hr), positive CRP (3.43mg/dl), positive ANA (x160), high titer of RA (266 IU/1), and a low titer of MPO-ANCA (18 EU). T 2-weighted magnetic resonance image (MRI) showed intensity area of the M. gastrocnemius. Skin biopsy specimens of the right leg demonstrated necrotizing arteritis of small-sized arteries. These findings supported the diagnosis of limited type of polyarteritis nodosa (PN). In this report, we demonstrate a rare case of PN limited to both calves with characteristic MRI findings and a low titer of MPO-ANCA.

AB - A-57-year-old woman had suffered from high fever, general malaise, and loss of weight (6 kg) since January, 2000. She was admitted to our hospital in May, 2000, because of gait disturbance following to swelling of bilateral calves with severe pain beside the above symptoms. Laboratory data showed leukocytosis (WBC 10,000/ μ1), high ESR (98 mm/hr), positive CRP (3.43mg/dl), positive ANA (x160), high titer of RA (266 IU/1), and a low titer of MPO-ANCA (18 EU). T 2-weighted magnetic resonance image (MRI) showed intensity area of the M. gastrocnemius. Skin biopsy specimens of the right leg demonstrated necrotizing arteritis of small-sized arteries. These findings supported the diagnosis of limited type of polyarteritis nodosa (PN). In this report, we demonstrate a rare case of PN limited to both calves with characteristic MRI findings and a low titer of MPO-ANCA.

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KW - Myeloperoxidase anti-neutrophil cytoplasmic antibody (MPO-ANCA)

KW - Polyarteritis nodosa

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A case of polyarteritis nodosa limited to both calves with a low titer of MPO-ANCA

Abstract

Keywords

ASJC Scopus subject areas

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