A case of pheochromocytoma accompanied with augmentation of growth hormone due to administration of growth hormone releasing hormone

Takashi Nagai, Yoshinori Mita, Masato Akiyama, Hiroaki Nakajima, Keiichi Itoi, Masatomo Mori

Research output: Contribution to journalArticlepeer-review

Abstract

A 28-year-old woman with right adrenal tumor had paroxysmal hypertension since 8 months ago. General laboratory data including urinalysis, hematology, liver function, renal function and electrolytes were normal. Urinary excretion of adrenaline, metanephrine and vanillylmandelic acid levels were elevated. In contrast, plasma adrenocorticotropic hormone, cortisol, aldosterone, parathyroid hormone, calcitonin and gastrin levels and urinary noradrenaline and normetanephrine levels were within the normal range. Normal growth hormone (GH) response to oral glucose ingestion test and thyrotropin releasing hormone-luteinizing hormone releasing hormone test was shown, however, augmentation of growth hormone (GH) response to GH releasing hormone (GHRH) was recognized. After removal of the tumor, which was compatible to pheochromocytoma histologically, her blood pressure, urinary excretion of catecholamine levels and augmentation of GH response to GHRH were normalized. It is concluded that augmentation of GH response to GHRH was due to pheochromocytoma.

Original languageEnglish
Pages (from-to)183-186
Number of pages4
JournalKitakanto Medical Journal
Volume49
Issue number3
DOIs
Publication statusPublished - 1999 Jan 1

Keywords

  • Augmentation of growth hormone
  • Growth hormone
  • Growth hormone releasing hormone
  • Hypertension
  • Pheochromocytoma

ASJC Scopus subject areas

  • Medicine(all)

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