A case of obesity, diabetes and hypertension treated with Very Low Calorie Diet (VLCD) followed by successful pregnancy with Intrauterine Insemination (IUI)

Akira Katsuki, Yasuhiro Sumida, Kuninobu Ito, Shuichi Murashima, Esteban C. Gabazza, Masahiko Furuta, Yutaka Yano, Takashi Sugiyama, Nagayasu Toyoda, Yukihiko Adachi

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

The patient was a 32-year-old obese woman with a history of type 2 diabetes and hypertension for 6 years. Although she was treated with antihypertensive agents and intensive insulin therapy, her hyperglycemia was difficult to control. She wanted to have a baby but pregnancy was not recommended because her diabetes was under poor control and the use of antihypertensive medication. To achieve good control of obesity, diabetes and hypertension, she was admitted to our clinical department for weight reduction using very low calorie diet (VLCD). During VLCD she had a 19.8 kg reduction in body weight and her blood glucose and blood pressure were in good control without the use of drugs. Five months later, she became pregnant after the fourth trial of intrauterine insemination (IUI) and gave birth to a female baby under insulin therapy. This is the first report that showed the usefulness of VLCD for prepregnant control of glucose metabolism and blood pressure in an obese hypertensive patient with type 2 diabetes mellitus.

Original languageEnglish
Pages (from-to)787-791
Number of pages5
Journalendocrine journal
Volume47
Issue number6
DOIs
Publication statusPublished - 2000

Keywords

  • Hypertension
  • Obesity
  • Pregnancy
  • Type 2 diabetes mellitus
  • Very low calorie diet

ASJC Scopus subject areas

  • Endocrinology, Diabetes and Metabolism
  • Endocrinology

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