A case of neuro-Behçet's disease with HLA B54 and predominant cerebral white matter lesions

K. Iwatsuki, K. Deguchi, H. Narai, T. Hayashi, H. Warita, Y. Manabe, K. Kashihara, K. Abe

Research output: Contribution to journalArticle

6 Citations (Scopus)

Abstract

We report a 55-year-old woman with neuro-Behçet's disease with HLA B54 and predominant cerebral white matter lesions. She showed a cryptogenic high fever and cerebral cortical symptoms such as perseveration, limb-kinetic apraxia and dementia. CSF study showed an increase of cell count and protein and a decrease of sugar. MRI showed diffuse T2-high signal intensity mainly in the subcortical white matter of left parieto-occipital lobes and basal ganglia. Her clinical signs greatly improved after administration of prednisolone. Her HLA type was not B51 but B54. Though our patient did not completely satisfy clinical criteria for neither neuro-Behçet's disease nor Sweet's syndrome, she showed partial features of both Behçet's disease and Sweet's syndrome.

Original languageEnglish
Pages (from-to)921-925
Number of pages5
JournalClinical Neurology
Volume40
Issue number9
Publication statusPublished - 2000 Dec 1
Externally publishedYes

Keywords

  • HLA B51
  • HLA B54
  • Neuro-Behçet's disease
  • Sweet's syndrome

ASJC Scopus subject areas

  • Clinical Neurology

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  • Cite this

    Iwatsuki, K., Deguchi, K., Narai, H., Hayashi, T., Warita, H., Manabe, Y., Kashihara, K., & Abe, K. (2000). A case of neuro-Behçet's disease with HLA B54 and predominant cerebral white matter lesions. Clinical Neurology, 40(9), 921-925.