A case of myelolipoma with bilateral adrenal hyperaldosteronism cured after unilateral adrenalectomy

Megumi Inuzuka, Naohisa Tamura, Masakatsu Sone, Daisuke Taura, Takuhiro Sonoyama, Kyoko Honda, Katsutoshi Kojima, Yorihide Fukuda, Yoriko Ueda, Yui Yamashita, Eri Kondo, Go Yamada, Toshihito Fujii, Masako Miura, Naotetsu Kanamoto, Akihiro Yasoda, Hiroshi Arai, Yoshiki Mikami, Hironobu Sasano, Kazuwa Nakao

Research output: Contribution to journalArticlepeer-review

5 Citations (Scopus)

Abstract

Myelolipomas are adrenal tumors composed of both adipose and hematopoietic tissues which are rarely associated with primary aldosteronism (PA). Here, we report a case of myelolipoma associated with PA. Aldosterone hypersecretion from bilateral adrenal glands had been confirmed by adrenal venous sampling and pathological analyses, but PA was clinically cured after surgical removal of the unilateral adrenal gland together with the myelolipoma that was not producing aldosterone. It is suggested that myelolipomas may release some factors which stimulate aldosterone production in adrenal glands, although further investigation is necessary. Obesity-related hyperaldosteronism might in part participate in generation of hypertension in the present case.

Original languageEnglish
Pages (from-to)479-485
Number of pages7
JournalInternal Medicine
Volume51
Issue number5
DOIs
Publication statusPublished - 2012

Keywords

  • Aldosterone-releasing factor
  • Bilateral adrenal hyperplasia
  • Myelolipoma
  • Primary aldosteronism

ASJC Scopus subject areas

  • Internal Medicine

Fingerprint Dive into the research topics of 'A case of myelolipoma with bilateral adrenal hyperaldosteronism cured after unilateral adrenalectomy'. Together they form a unique fingerprint.

Cite this