A case of multiple gastric carcinoid associated with hypergastrinemia

Makoto Kinouchi, Kenichi Shiiba, Seiichi Ishii, Takayuki Mizoi, Jun Oyama, Seiki Matsuno, Iwao Sasaki

Research output: Contribution to journalArticlepeer-review

1 Citation (Scopus)

Abstract

We report a case of multiple gastric carcinoid with hypergastrinemia. A 38-year-old man found to have an abnormality of the stomach in a medical check up was found in gastric endoscopy to have multiple polyps from the gastric fornix to the middle gastric body. Polyp biopsy showed them to be carcinoid, so he referred to our hospital for further study. Laboratory data showed hypergastrinemia (serum gastrin of 800pg/dl), but normal serum serotonin. Acid endocrine test by gastroscopy shows no acid pattern. Endosonography showed the depth of invasion to be submucosal layer, so we conducted total gastrectomy with lymph node dissection due to the possibility of lymph node metastasis. Histological examination reveals the three largest polyps as carcinoid, and the other polyps as hyperplastic polyp. Also it reveals the maximum carcinoid as sm, n0, v1 and ly0, and the other carcinoids as m. Postoperative laboratory data showed that the serum gastrin had normalized (25pg/ml). To determine therapy for gastric carcinoid. we must consider factors such as size and depth of invasion.

Original languageEnglish
Pages (from-to)1616-1621
Number of pages6
JournalJapanese Journal of Gastroenterological Surgery
Volume37
Issue number10
DOIs
Publication statusPublished - 2004

Keywords

  • Gastric carcinoid
  • Hyper gastrinemia
  • Type A gastritis

ASJC Scopus subject areas

  • Surgery
  • Gastroenterology

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