A case of moyamoya disease presenting with chorea

Wei Zheng, Masahiko Wanibuchi, Toshiaki Onda, He Liu, Izumi Koyanagi, Kenji Fujimori, Kiyohiro Houkin

Research output: Contribution to journalArticlepeer-review

20 Citations (Scopus)


Case report: We describe a 15-year-old girl with moyamoya disease whose initial manifestation was chorea-like involuntary movements. T2-weighted magnetic resonance imaging showed high signal intensity lesions in the left frontal lobe, right parieto-occipital lobes, and frontal subcortical white matter. Single-photon emission computed tomography (SPECT) showed diffuse hypoperfusion of the whole brain. Bilateral direct and indirect cerebrovascular bypass surgeries were performed. Chorea disappeared 2 days after the surgery. Follow-up SPECT demonstrated increased cerebral perfusion in the bilateral frontal, temporal, and parietal regions. Conclusions: Chorea accompanied with moyamoya disease can be properly managed by revascularization surgery. Moyamoya disease should be remembered as being one of the differential diagnoses of chorea, which is treatable by surgery.

Original languageEnglish
Pages (from-to)274-278
Number of pages5
JournalChild's Nervous System
Issue number3
Publication statusPublished - 2006 Mar
Externally publishedYes


  • Cerebral perfusion
  • Chorea
  • Involuntary movements
  • Ischemia
  • Moyamoya disease
  • Subcortical white matter
  • Surgical treatment

ASJC Scopus subject areas

  • Pediatrics, Perinatology, and Child Health
  • Clinical Neurology

Fingerprint Dive into the research topics of 'A case of moyamoya disease presenting with chorea'. Together they form a unique fingerprint.

Cite this