A case of hepatocellular carcinoma with lumbar bone metastasis with high uptake of 18F-fluorodexoygalatose in PET

H. Fukuda, S. Yoshioka, J. Takahashi, Ryoui Goto, M. Tada, K. Murata, T. Fujiwara, M. Itoh, Ren Iwata, T. Ido

Research output: Contribution to journalArticlepeer-review

4 Citations (Scopus)

Abstract

18F-fluorodeoxygalactose (18FDGal) is a tracer for the evaluation of galactose metabolism in the tissue. PET with 18FDGal was performed in a hepatoma (HCC) patient with lumbar bone metastasis. The image at 45 min after i.v. injection of 18FDGal demonstrated very high uptake by the bone metastasis with tumor-to-surrounding normal tissue ratio of 36. The tumor uptake expressed by differential absorption ratio was much higher than that in the cirrhotic liver and kidney. The result indicated that the HCC maintained high activity of galactose metabolism and rises the potential of this tracer for detecting extrahepatic metastases of HCC using PET.

Original languageEnglish
Pages (from-to)1351-1355
Number of pages5
JournalKakuigaku
Volume31
Issue number11
Publication statusPublished - 1994 Dec 1

Keywords

  • HCC
  • PET
  • galactose metabolism
  • metastasis

ASJC Scopus subject areas

  • Radiology Nuclear Medicine and imaging

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