A case of fulminant hepatic failure in an elderly asymptomatic HBV carrier without proximate cause

Takeshi Yamamoto; Shiho Kondo; Akiko Sugawara; Makoto Yonechi; Kana Nishioka; Takayoshi Meguro; Masahide Abe; Kazuhiro Murakami; Jun Inoue; Yoshiyuki Ueno; Toru Shimosegawa

A case of fulminant hepatic failure in an elderly asymptomatic HBV carrier without proximate cause

Takeshi Yamamoto, Shiho Kondo, Akiko Sugawara, Makoto Yonechi, Kana Nishioka, Takayoshi Meguro, Masahide Abe, Kazuhiro Murakami, Jun Inoue, Yoshiyuki Ueno, Toru Shimosegawa

Research output: Contribution to journal › Article › peer-review

1 Citation (Scopus)

Abstract

A 82-year-old asymptomatic HBV carrier man was admitted with liver dysfunction in May 2007. With anti-HBe antibody and high viral load, he had fulminant hepatic failure without proximate cause. He was treated with entecavir and corticosteroids, but died about one month later. Autopsy specimen of liver revealed submassive hepatic necrosis with faint regeneration. HBV obtained was segregated into genotype Bj, and mutation was detected at nt1896 in a precore region.

Original language	English
Pages (from-to)	1781-1786
Number of pages	6
Journal	Japanese Journal of Gastroenterology
Volume	105
Issue number	12
Publication status	Published - 2008
Externally published	Yes

ASJC Scopus subject areas

Gastroenterology

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A case of fulminant hepatic failure in an elderly asymptomatic HBV carrier without proximate cause. / Yamamoto, Takeshi; Kondo, Shiho; Sugawara, Akiko; Yonechi, Makoto; Nishioka, Kana; Meguro, Takayoshi; Abe, Masahide; Murakami, Kazuhiro; Inoue, Jun; Ueno, Yoshiyuki; Shimosegawa, Toru.

In: Japanese Journal of Gastroenterology, Vol. 105, No. 12, 2008, p. 1781-1786.

Research output: Contribution to journal › Article › peer-review

Yamamoto, Takeshi ; Kondo, Shiho ; Sugawara, Akiko ; Yonechi, Makoto ; Nishioka, Kana ; Meguro, Takayoshi ; Abe, Masahide ; Murakami, Kazuhiro ; Inoue, Jun ; Ueno, Yoshiyuki ; Shimosegawa, Toru. / A case of fulminant hepatic failure in an elderly asymptomatic HBV carrier without proximate cause. In: Japanese Journal of Gastroenterology. 2008 ; Vol. 105, No. 12. pp. 1781-1786.

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abstract = "A 82-year-old asymptomatic HBV carrier man was admitted with liver dysfunction in May 2007. With anti-HBe antibody and high viral load, he had fulminant hepatic failure without proximate cause. He was treated with entecavir and corticosteroids, but died about one month later. Autopsy specimen of liver revealed submassive hepatic necrosis with faint regeneration. HBV obtained was segregated into genotype Bj, and mutation was detected at nt1896 in a precore region.",

author = "Takeshi Yamamoto and Shiho Kondo and Akiko Sugawara and Makoto Yonechi and Kana Nishioka and Takayoshi Meguro and Masahide Abe and Kazuhiro Murakami and Jun Inoue and Yoshiyuki Ueno and Toru Shimosegawa",

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AU - Yamamoto, Takeshi

AU - Kondo, Shiho

AU - Sugawara, Akiko

AU - Yonechi, Makoto

AU - Nishioka, Kana

AU - Meguro, Takayoshi

AU - Abe, Masahide

AU - Murakami, Kazuhiro

AU - Inoue, Jun

AU - Ueno, Yoshiyuki

AU - Shimosegawa, Toru

PY - 2008

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N2 - A 82-year-old asymptomatic HBV carrier man was admitted with liver dysfunction in May 2007. With anti-HBe antibody and high viral load, he had fulminant hepatic failure without proximate cause. He was treated with entecavir and corticosteroids, but died about one month later. Autopsy specimen of liver revealed submassive hepatic necrosis with faint regeneration. HBV obtained was segregated into genotype Bj, and mutation was detected at nt1896 in a precore region.

AB - A 82-year-old asymptomatic HBV carrier man was admitted with liver dysfunction in May 2007. With anti-HBe antibody and high viral load, he had fulminant hepatic failure without proximate cause. He was treated with entecavir and corticosteroids, but died about one month later. Autopsy specimen of liver revealed submassive hepatic necrosis with faint regeneration. HBV obtained was segregated into genotype Bj, and mutation was detected at nt1896 in a precore region.

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SN - 0446-6586

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ER -

A case of fulminant hepatic failure in an elderly asymptomatic HBV carrier without proximate cause

Abstract

ASJC Scopus subject areas

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