A case of fulminant hepatic failure in an elderly asymptomatic HBV carrier without proximate cause

Takeshi Yamamoto, Shiho Kondo, Akiko Sugawara, Makoto Yonechi, Kana Nishioka, Takayoshi Meguro, Masahide Abe, Kazuhiro Murakami, Jun Inoue, Yoshiyuki Ueno, Toru Shimosegawa

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Abstract

A 82-year-old asymptomatic HBV carrier man was admitted with liver dysfunction in May 2007. With anti-HBe antibody and high viral load, he had fulminant hepatic failure without proximate cause. He was treated with entecavir and corticosteroids, but died about one month later. Autopsy specimen of liver revealed submassive hepatic necrosis with faint regeneration. HBV obtained was segregated into genotype Bj, and mutation was detected at nt1896 in a precore region.

Original languageEnglish
Pages (from-to)1781-1786
Number of pages6
JournalJapanese Journal of Gastroenterology
Volume105
Issue number12
Publication statusPublished - 2008

ASJC Scopus subject areas

  • Gastroenterology

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    Yamamoto, T., Kondo, S., Sugawara, A., Yonechi, M., Nishioka, K., Meguro, T., Abe, M., Murakami, K., Inoue, J., Ueno, Y., & Shimosegawa, T. (2008). A case of fulminant hepatic failure in an elderly asymptomatic HBV carrier without proximate cause. Japanese Journal of Gastroenterology, 105(12), 1781-1786.