A case of central retinal vein occlusion complicated with hemophilia A

Shin Ichi Abe, Hisae Nishikatsu, Tomoki Yasui, Takayuki Takeshita

Research output: Contribution to journalArticlepeer-review


Recently, we treated a patient with occlusion of the central retinal vein whose treatment was complicated by hemophilia A, which results from congenital lack of blood coagulation factor VIII. The patient, a 47-year-old male, presented with central retinal vein occlusion in the right eye and macular degeneration in the left eye. Analysis of blood components showed that his activated partial thromboplastin time (APTT) was prolonged to 50.7 sec and the activity factor VIII was decreased to 5%. We transfused factor VIII concentrate, and blood values normalized with a decrease in APTT to 39.0 sec and an increase in factor VIII activity to 40%. In addition, bleeding in the fundus gradually disappeared and has not recurred.

Original languageEnglish
Pages (from-to)47-50
Number of pages4
JournalFolia Ophthalmologica Japonica
Issue number1
Publication statusPublished - 1998


  • Central Retinal Vein Occlusion
  • Factor VIII Concentrate
  • Hemophilia A
  • Macular Degeneration

ASJC Scopus subject areas

  • Ophthalmology


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