A case of bilateral diffuse uveal melanocytic proliferation in a patient with cholangiocarcinoma that responded to corticosteroid treatment

Hiroshi Miyazawa, Hajime Sato, Hidetoshi Takahashi, Ryosuke Wakusawa, Koji Nishida

Research output: Contribution to journalArticlepeer-review

Abstract

Background: We report a case of bilateral diffuse uveal melanocytic proliferation (BDUMP) that responded to corticosteroid treatment. Case Report: A 46-year-old female noticed vision changes in both eyes after surgery for cholangiocarcinoma. At the initial ophthalmologic examination, best-corrected visual acuity (BCVA) was 1.2 in the right eye and 2.0 in the left. Findings on anterior and posterior segment examinations were unremarkable. About 9 weeks later, BCVA deteriorated to 0.4 in the right eye and 0.2 in the left. Funduscopy revealed bilateral exudative retinal detachment and bilateral multiple, round or oval, subtle, yellowish white patches at the level of the retinal pigment epithelium. On fluorescein angiography there was early hyperfluorescence in areas corresponding to the patches. We diagnosed BDUMP and prescribed a course of corticosteroid treatment. After the treatment, exudative retinal detachment resolved in both eyes and BCVA improved to 1.2 in the right eye and 1.5 in the left. Conclusions: Some cases of BDUMP respond to corticosteroid treatment.

Original languageEnglish
Pages (from-to)35-39
Number of pages5
JournalFolia Ophthalmologica Japonica
Volume58
Issue number1
Publication statusPublished - 2007 Jan

Keywords

  • Bilateral Diffuse Uveal Melanocytic Proliferation (BDUMP)
  • Corticosteroid

ASJC Scopus subject areas

  • Ophthalmology

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