A case of advanced gastric and rectal cancer (double cancer) successfully treated with mFOLFOX6 therapy

Tadashi Ishii; Iwao Kaneda; Akihiko Furuta; Masaru Shoji; Satoru Ishibashi; Kazuaki Hatsugai; Masato Ohara; Hiroki Sarashina; Hiroo Masuoka; Yuki Sekine; Go Watanabe

A case of advanced gastric and rectal cancer (double cancer) successfully treated with mFOLFOX6 therapy

Tadashi Ishii, Iwao Kaneda, Akihiko Furuta, Masaru Shoji, Satoru Ishibashi, Kazuaki Hatsugai, Masato Ohara, Hiroki Sarashina, Hiroo Masuoka, Yuki Sekine, Go Watanabe

Research output: Contribution to journal › Article › peer-review

Abstract

A 75-year-old man was diagnosed with gastric cancer (UL post c0-IIc (cT1N0) and M-less ctype II (cT2N0)) and rectal cancer (Rb ctype II (cT2N1) with multiple lung metastases (M1). The patient was treated with modified (m) FOLFOX6 regimen (oxaliplatin in combination with infusional 5-fluorouracil/Leucovorin). Chest and abdominal CT scan revealed that multiple lung metastases and abdominal lymph node metastases were obviously reduced in size. The primary lesion of the rectum almost disappeared on endoscopic examination. As for the lesions of the stomach, the UL post c0-IIc lesion completely disappeared, and the M-less ctype II lesion was reduced remarkably. Thus, a significant reduction of the tumors was observed. This case suggests that mFOLFOX6 regimen can be an option for gastric cancer.

Original language	English
Pages (from-to)	1171-1174
Number of pages	4
Journal	Japanese Journal of Cancer and Chemotherapy
Volume	36
Issue number	7
Publication status	Published - 2009 Jul
Externally published	Yes

Keywords

Chemotherapy
Gastric cancer
mFOLFOX

ASJC Scopus subject areas

Oncology
Cancer Research

UN SDGs

This output contributes to the following UN Sustainable Development Goals (SDGs)

Cite this

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title = "A case of advanced gastric and rectal cancer (double cancer) successfully treated with mFOLFOX6 therapy",

abstract = "A 75-year-old man was diagnosed with gastric cancer (UL post c0-IIc (cT1N0) and M-less ctype II (cT2N0)) and rectal cancer (Rb ctype II (cT2N1) with multiple lung metastases (M1). The patient was treated with modified (m) FOLFOX6 regimen (oxaliplatin in combination with infusional 5-fluorouracil/Leucovorin). Chest and abdominal CT scan revealed that multiple lung metastases and abdominal lymph node metastases were obviously reduced in size. The primary lesion of the rectum almost disappeared on endoscopic examination. As for the lesions of the stomach, the UL post c0-IIc lesion completely disappeared, and the M-less ctype II lesion was reduced remarkably. Thus, a significant reduction of the tumors was observed. This case suggests that mFOLFOX6 regimen can be an option for gastric cancer.",

keywords = "Chemotherapy, Gastric cancer, mFOLFOX",

author = "Tadashi Ishii and Iwao Kaneda and Akihiko Furuta and Masaru Shoji and Satoru Ishibashi and Kazuaki Hatsugai and Masato Ohara and Hiroki Sarashina and Hiroo Masuoka and Yuki Sekine and Go Watanabe",

year = "2009",

month = jul,

language = "English",

volume = "36",

pages = "1171--1174",

journal = "Japanese Journal of Cancer and Chemotherapy",

issn = "0385-0684",

publisher = "Japanese Journal of Cancer and Chemotherapy Publishers Inc.",

number = "7",

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TY - JOUR

T1 - A case of advanced gastric and rectal cancer (double cancer) successfully treated with mFOLFOX6 therapy

AU - Ishii, Tadashi

AU - Kaneda, Iwao

AU - Furuta, Akihiko

AU - Shoji, Masaru

AU - Ishibashi, Satoru

AU - Hatsugai, Kazuaki

AU - Ohara, Masato

AU - Sarashina, Hiroki

AU - Masuoka, Hiroo

AU - Sekine, Yuki

AU - Watanabe, Go

PY - 2009/7

Y1 - 2009/7

N2 - A 75-year-old man was diagnosed with gastric cancer (UL post c0-IIc (cT1N0) and M-less ctype II (cT2N0)) and rectal cancer (Rb ctype II (cT2N1) with multiple lung metastases (M1). The patient was treated with modified (m) FOLFOX6 regimen (oxaliplatin in combination with infusional 5-fluorouracil/Leucovorin). Chest and abdominal CT scan revealed that multiple lung metastases and abdominal lymph node metastases were obviously reduced in size. The primary lesion of the rectum almost disappeared on endoscopic examination. As for the lesions of the stomach, the UL post c0-IIc lesion completely disappeared, and the M-less ctype II lesion was reduced remarkably. Thus, a significant reduction of the tumors was observed. This case suggests that mFOLFOX6 regimen can be an option for gastric cancer.

AB - A 75-year-old man was diagnosed with gastric cancer (UL post c0-IIc (cT1N0) and M-less ctype II (cT2N0)) and rectal cancer (Rb ctype II (cT2N1) with multiple lung metastases (M1). The patient was treated with modified (m) FOLFOX6 regimen (oxaliplatin in combination with infusional 5-fluorouracil/Leucovorin). Chest and abdominal CT scan revealed that multiple lung metastases and abdominal lymph node metastases were obviously reduced in size. The primary lesion of the rectum almost disappeared on endoscopic examination. As for the lesions of the stomach, the UL post c0-IIc lesion completely disappeared, and the M-less ctype II lesion was reduced remarkably. Thus, a significant reduction of the tumors was observed. This case suggests that mFOLFOX6 regimen can be an option for gastric cancer.

KW - Chemotherapy

KW - Gastric cancer

KW - mFOLFOX

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UR - http://www.scopus.com/inward/citedby.url?scp=79959840438&partnerID=8YFLogxK

M3 - Article

C2 - 19620811

AN - SCOPUS:79959840438

VL - 36

SP - 1171

EP - 1174

JO - Japanese Journal of Cancer and Chemotherapy

JF - Japanese Journal of Cancer and Chemotherapy

SN - 0385-0684

IS - 7

ER -

A case of advanced gastric and rectal cancer (double cancer) successfully treated with mFOLFOX6 therapy

Abstract

Keywords

ASJC Scopus subject areas

UN SDGs

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