A case of adenoendocrine cell carcinoma of the ampulla of Vater

Tomoya Abe; Tetsuyuki Uchiyama; Masaru Onuma; Taku Kitayama; Takashi Kato; Yasuhiko Kamiyama; Hideo Ise; Mika Watanabe

doi:10.5833/jjgs.40.605

A case of adenoendocrine cell carcinoma of the ampulla of Vater

Tomoya Abe, Tetsuyuki Uchiyama, Masaru Onuma, Taku Kitayama, Takashi Kato, Yasuhiko Kamiyama, Hideo Ise, Mika Watanabe

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Abstract

A 73-year-old man admitted for obstructive jaundice was found in histological examination of a biopsied specimen of the papilla of Vater to have adenocarcinoma. We conducted pancreaticoduodenectomy with regional lymph node dissection. Histologically, the tumor consisted of solid nests of eosinophilic atypical cells with adenocarcinoma. Immunohistochemically, staining was positive for NSE and chromogranin A. The definitive diagnosis was adenoendocrine cell carcinoma. Although the prognosis of endocrine cell carcinoma is ordinarily dismal, the man has remained disease-free in the 14 months since surgery, presumably thanks to adjuvant chemotherapy. To the best of our knowledge, this is the only seventh case ever reported of endocrine cell carcinoma of the ampulla of Vater in Japan.

Original language	English
Pages (from-to)	605-610
Number of pages	6
Journal	Japanese Journal of Gastroenterological Surgery
Volume	40
Issue number	5
DOIs	https://doi.org/10.5833/jjgs.40.605
Publication status	Published - 2007 May
Externally published	Yes

Keywords

Adenoendocrine cell carcinoma
Adjuvant chemotherapy
Ampulla of Vater

ASJC Scopus subject areas

Surgery
Gastroenterology

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10.5833/jjgs.40.605

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title = "A case of adenoendocrine cell carcinoma of the ampulla of Vater",

abstract = "A 73-year-old man admitted for obstructive jaundice was found in histological examination of a biopsied specimen of the papilla of Vater to have adenocarcinoma. We conducted pancreaticoduodenectomy with regional lymph node dissection. Histologically, the tumor consisted of solid nests of eosinophilic atypical cells with adenocarcinoma. Immunohistochemically, staining was positive for NSE and chromogranin A. The definitive diagnosis was adenoendocrine cell carcinoma. Although the prognosis of endocrine cell carcinoma is ordinarily dismal, the man has remained disease-free in the 14 months since surgery, presumably thanks to adjuvant chemotherapy. To the best of our knowledge, this is the only seventh case ever reported of endocrine cell carcinoma of the ampulla of Vater in Japan.",

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AU - Abe, Tomoya

AU - Uchiyama, Tetsuyuki

AU - Onuma, Masaru

AU - Kitayama, Taku

AU - Kato, Takashi

AU - Kamiyama, Yasuhiko

AU - Ise, Hideo

AU - Watanabe, Mika

PY - 2007/5

Y1 - 2007/5

N2 - A 73-year-old man admitted for obstructive jaundice was found in histological examination of a biopsied specimen of the papilla of Vater to have adenocarcinoma. We conducted pancreaticoduodenectomy with regional lymph node dissection. Histologically, the tumor consisted of solid nests of eosinophilic atypical cells with adenocarcinoma. Immunohistochemically, staining was positive for NSE and chromogranin A. The definitive diagnosis was adenoendocrine cell carcinoma. Although the prognosis of endocrine cell carcinoma is ordinarily dismal, the man has remained disease-free in the 14 months since surgery, presumably thanks to adjuvant chemotherapy. To the best of our knowledge, this is the only seventh case ever reported of endocrine cell carcinoma of the ampulla of Vater in Japan.

AB - A 73-year-old man admitted for obstructive jaundice was found in histological examination of a biopsied specimen of the papilla of Vater to have adenocarcinoma. We conducted pancreaticoduodenectomy with regional lymph node dissection. Histologically, the tumor consisted of solid nests of eosinophilic atypical cells with adenocarcinoma. Immunohistochemically, staining was positive for NSE and chromogranin A. The definitive diagnosis was adenoendocrine cell carcinoma. Although the prognosis of endocrine cell carcinoma is ordinarily dismal, the man has remained disease-free in the 14 months since surgery, presumably thanks to adjuvant chemotherapy. To the best of our knowledge, this is the only seventh case ever reported of endocrine cell carcinoma of the ampulla of Vater in Japan.

KW - Adenoendocrine cell carcinoma

KW - Adjuvant chemotherapy

KW - Ampulla of Vater

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A case of adenoendocrine cell carcinoma of the ampulla of Vater

Abstract

Keywords

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