Abstract
A boron-dipyrromethene (BODIPY) derivative with a hydroxymethyl group at the meso-position, 1, was synthesized, which exhibits a highly specific and rapid 'turn-off' response for HOCl during confocal fluorescence microscopy experiments under physiological conditions and in live cells. The formation of an electron-withdrawing formyl substituent upon oxidation results in highly efficient nonradiative decay of the S1 state and hence in a drastic decrease in fluorescence emission intensity.
Original language | English |
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Pages (from-to) | 1-6 |
Number of pages | 6 |
Journal | Sensors and Actuators, B: Chemical |
Volume | 182 |
DOIs | |
Publication status | Published - 2013 |
Externally published | Yes |
Keywords
- BODIPY
- Cell image
- Fluorescent probe
- Hypochlorous acid
- TD-DFT
ASJC Scopus subject areas
- Electronic, Optical and Magnetic Materials
- Instrumentation
- Condensed Matter Physics
- Surfaces, Coatings and Films
- Metals and Alloys
- Electrical and Electronic Engineering
- Materials Chemistry