A novel naphthalenophane, 1,12-dioxa(1,4)naphthalenophane-14-carboxylic acid (1), is conveniently prepared from 1,4-dihydroxy-2-naphthoic acid and 1,10-dibromodecane. Acid 1 is resolved by crystallization of its quinine or quinidine salt, and the absolute stereochemistry of acid (-)-1 is determined to be S by the X-ray crystallographic analysis of (1S,2R,4R)-(-)-2,10-camphorsultam) amide derivative (4).
ASJC Scopus subject areas
- Physical and Theoretical Chemistry
- Organic Chemistry
- Inorganic Chemistry