δ and γ tocotrienols suppress human hepatocellular carcinoma cell proliferation: Via regulation of Ras-Raf-MEK-ERK pathway-associated upstream signaling

Gregor Carpentero Burdeos, Junya Ito, Takahiro Eitsuka, Kiyotaka Nakagawa, Fumiko Kimura, Teruo Miyazawa

Research output: Contribution to journalArticlepeer-review

8 Citations (Scopus)

Abstract

Tocotrienol (T3) has recently gained increasing interest due to its anti-cancer effect. Here, we investigated the modulating effect of δ and γ T3 on the Ras-Raf-MEK-ERK oncogenic upstream signaling pathway in human hepatocellular carcinoma HepG2 cells. The results indicated that T3 regulated the upstream signaling cascades of this pathway.

Original languageEnglish
Pages (from-to)4170-4174
Number of pages5
JournalFood and Function
Volume7
Issue number10
DOIs
Publication statusPublished - 2016 Oct 1

ASJC Scopus subject areas

  • Food Science

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