α-FP normalization as a prognostic factor for mediastinal origin embryonal carcinoma: Report of five cases

Yasuko Murakawa, Nobuaki Satake, Syunsuke Kato, Takasi Yosioka, Ryunosuke Kanamaru

Research output: Contribution to journalArticlepeer-review

2 Citations (Scopus)

Abstract

It is well known that a subgroup of germ cell tumors, embryonal carcinoma of extra-gonadal origin have a poor prognosis. We have encountered five cases of mediastinal embryonal carcinoma treated with high-dose chemotherapy (HD-CT) supported by auto-PBSCT in four, and resection in three. Our cases indicated that normalization of the α-FP tumor marker level during standard chemotherapy is a very important factor for cure, and the resection of the residual mass after chemotherapy is indicated due to the great risk of remnant malignant cells despite HD-CT.

Original languageEnglish
Pages (from-to)883-888
Number of pages6
JournalInternal Medicine
Volume41
Issue number10
DOIs
Publication statusPublished - 2002 Oct 1

Keywords

  • Germ cell tumors (GCTs)
  • High-dose chemotherapy (HD-CT) supported by auto-PBSCT

ASJC Scopus subject areas

  • Internal Medicine

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