Abstract
A synthetically useful approach for the direct α-arylation of carbonyl compounds through a novel oxidative C−C bond activation is reported. This mechanistically unusual process relies on a 1,2-aryl shift and results in all-carbon quaternary centers. The transformation displays broad functional-group tolerance and can in principle also be applied as an asymmetric variant.
Original language | English |
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Pages (from-to) | 9816-9819 |
Number of pages | 4 |
Journal | Angewandte Chemie - International Edition |
Volume | 58 |
Issue number | 29 |
DOIs | |
Publication status | Published - 2019 Jul 15 |
Externally published | Yes |
Keywords
- C−C bond activation
- arylation
- enolonium species
- ketones
- umpolung
ASJC Scopus subject areas
- Catalysis
- Chemistry(all)