Yujiro Hayashi

Professor

  • 11167 Citations
  • 54 h-Index
1989 …2020

Research output per year

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Research Output

2020

Asymmetric One-Pot Mukaiyama Michael/Michael Reaction Catalyzed by Diphenylprolinol Silyl Ether

Umekubo, N. & Hayashi, Y., 2020 Sep 14, In : European Journal of Organic Chemistry. 2020, 34, p. 5596-5600 5 p.

Research output: Contribution to journalArticle

Asymmetric Synthesis of Corey Lactone and Latanoprost

Umekubo, N. & Hayashi, Y., 2020, (Accepted/In press) In : European Journal of Organic Chemistry.

Research output: Contribution to journalArticle

Domino and one-pot syntheses of biologically active compounds using diphenylprolinol silyl ether

Hayashi, Y., 2020 Jan 1, (Accepted/In press) In : Physical Sciences Reviews. 2018-0088.

Research output: Contribution to journalArticle

Highly enantioselective access to syn-α,γ-dihydroxycarbonyl building blocks via organocatalyst-mediated aldol reaction as a key step

Hayashi, Y., Wang, X. & Kawauchi, G., 2020 Aug 5, In : Chemistry Letters. 49, 8, p. 940-943 4 p.

Research output: Contribution to journalArticle

Inversion of the Axial Information during Oxidative Aromatization in the Synthesis of Axially Chiral Biaryls with Organocatalysis as a Key Step

Koshino, S., Takikawa, A., Ishida, K., Taniguchi, T., Monde, K., Kwon, E., Umemiya, S. & Hayashi, Y., 2020 Apr 6, In : Chemistry (Weinheim an der Bergstrasse, Germany). 26, 20, p. 4524-4530 7 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Inversion of the Axial Information during Oxidative Aromatization in the Synthesis of Axially Chiral Biaryls with Organocatalysis as a Key Step

Koshino, S., Takikawa, A., Ishida, K., Taniguchi, T., Monde, K., Kwon, E., Umemiya, S. & Hayashi, Y., 2020 Apr 6, In : Chemistry - A European Journal. 26, 20, p. 4436 1 p.

Research output: Contribution to journalComment/debate

Open Access

One-pot Synthesis of Chiral cis-Hydrindanes via Diphenylprolinol Silyl Ether Mediated Domino Reaction and Aldol Condensation

Umekubo, N., Iwata, R. & Hayashi, Y., 2020 Jul, In : Chemistry Letters. 49, 7, p. 867-869 3 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Pot and time economies in the total synthesis of Corey lactone

Umekubo, N., Suga, Y. & Hayashi, Y., 2020 Jan 1, In : Chemical Science. 11, 5, p. 1205-1209 5 p.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)
2019

Asymmetric Michael Reaction of α-CF3 Thioester and α,β-Unsaturated Aldehyde Catalyzed by Diphenylprolinol Silyl Ether

Hayashi, Y., Yamada, T., Sato, M., Watanabe, S., Kwon, E., Iwasaki, K. & Umemiya, S., 2019 Jun 18, In : Organic letters. 21, 13, p. 5183-5186 4 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Asymmetric Synthesis of Biaryl Atropisomers Using an Organocatalyst-Mediated Domino Reaction as the Key Step

Hayashi, Y., Takikawa, A., Koshino, S. & Ishida, K., 2019 Jan 1, In : Chemistry - A European Journal. 25, 44, p. 10319-10322 4 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)
Open Access
1 Citation (Scopus)
1 Citation (Scopus)
7 Citations (Scopus)
2018

Asymmetric michael reaction of aldehyde and β-substituted α-nitroacrylate catalyzed by diphenylprolinol silyl ether

Sakamoto, D. & Hayashi, Y., 2018 Jan 1, In : Chemistry Letters. 47, 7, p. 833-835 3 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Asymmetric Michael Reaction of Aldehydes and Dicyanoalkenes Catalyzed by Diphenylprolinol Silyl Ether

Hayashi, Y., Kranidiotis-Hisatomi, N., Sakamoto, D., Oritani, K., Kawamoto, T. & Kamimura, A., 2018 Dec 31, In : European Journal of Organic Chemistry. 2018, 48, p. 6843-6847 5 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)

Asymmetric Michael reaction of aldehydes and nitroalkenes

Hayashi, Y., Ogasawara, S., Ueda, Y. & Suzuki, K., 2018 Jun 20, In : Organic Syntheses. 94

Research output: Contribution to journalArticle

Autoinductive conversion of α,α-diiodonitroalkanes to amides and esters catalysed by iodine byproducts under O2

Li, J., Lear, M. J. & Hayashi, Y., 2018, In : Chemical Communications. 54, 49, p. 6360-6363 4 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
14 Citations (Scopus)

Enantio- and Diastereoselective Synthesis of Latanoprost using an Organocatalyst

Kawauchi, G., Umemiya, S., Taniguchi, T., Monde, K. & Hayashi, Y., 2018 Jun 12, In : Chemistry - A European Journal. 24, 33, p. 8409-8414 6 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Prolinate Salt as a Catalyst in the syn -Selective, Asymmetric Mannich Reaction of Alkynyl Imine

Hayashi, Y., Yamazaki, T., Kawauchi, G. & Sato, I., 2018 Apr 20, In : Organic letters. 20, 8, p. 2391-2394 4 p.

Research output: Contribution to journalArticle

11 Citations (Scopus)

Synthetic Studies on Presporolide, a Putative Enediyne Precursor of Sporolides

Yamashita, S., Terayama, K., Ozeki, E., Hayashi, Y. & Hirama, M., 2018 Jan 5, In : Organic letters. 20, 1, p. 276-279 4 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Total Synthesis of Estradiol Methyl Ether and Its Five-Pot Synthesis with an Organocatalyst

Koshino, S., Kwon, E. & Hayashi, Y., 2018 Nov 8, In : European Journal of Organic Chemistry. 2018, 41, p. 5629-5638 10 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Two-Pot Synthesis of Chiral 1,3-syn-Diols through Asymmetric Organocatalytic Aldol and Wittig Reactions Followed by Domino Hemiacetal/Oxy-Michael Reactions

Hayashi, Y., Saitoh, T., Arase, H., Kawauchi, G., Takeda, N., Shimasaki, Y. & Sato, I., 2018 Apr 3, In : Chemistry - A European Journal. 24, 19, p. 4909-4915 7 p.

Research output: Contribution to journalArticle

15 Citations (Scopus)
2017

Enantioselective Total Synthesis of Beraprost Using Organocatalyst

Umemiya, S., Sakamoto, D., Kawauchi, G. & Hayashi, Y., 2017 Mar 3, In : Organic letters. 19, 5, p. 1112-1115 4 p.

Research output: Contribution to journalArticle

16 Citations (Scopus)

Multistep Continuous-Flow Synthesis of (-)-Oseltamivir

Ogasawara, S. & Hayashi, Y., 2017 Jan 18, In : Synthesis (Germany). 49, 2, p. 424-428 5 p., ss-2016-z0587-op.

Research output: Contribution to journalArticle

18 Citations (Scopus)

Pot Economy in the Total Synthesis of Estradiol Methyl Ether by Using an Organocatalyst

Hayashi, Y., Koshino, S., Ojima, K. & Kwon, E., 2017 Jan 1, In : Angewandte Chemie - International Edition. 56, 39, p. 11812-11815 4 p.

Research output: Contribution to journalArticle

20 Citations (Scopus)

Prolinate Salts as Catalysts for α-Aminoxylation of Aldehyde and Associated Mechanistic Insights

Hayashi, Y., Umekubo, N. & Hirama, T., 2017 Aug 18, In : Organic letters. 19, 16, p. 4155-4158 4 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)
2016

16O/18O Exchange of Aldehydes and Ketones caused by H2 18O in the Mechanistic Investigation of Organocatalyzed Michael, Mannich, and Aldol Reactions

Hayashi, Y., Mukaiyama, T., Benohoud, M., Gupta, N. R., Ono, T. & Toda, S., 2016 Apr 18, In : Chemistry - A European Journal. 22, 17, p. 5868-5872 5 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)

Asymmetric Aldol Reaction of Dichloroacetaldehyde Catalyzed by Diarylprolinol

Hayashi, Y., Nakamura, D., Yasui, Y., Iwasaki, K. & Chiba, H., 2016 Jan 1, In : Advanced Synthesis and Catalysis. 358, 14, p. 2345-2351 7 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Asymmetric Diels–Alder Reaction of α-Substituted and β,β-Disubstituted α,β-Enals via Diarylprolinol Silyl Ether for the Construction of All-Carbon Quaternary Stereocenters

Hayashi, Y., Bondzic, B. P., Yamazaki, T., Gupta, Y., Ogasawara, S., Taniguchi, T. & Monde, K., 2016, In : Chemistry - A European Journal. 22, 44, p. 15874-15880 7 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Enantioselective Total Synthesis of RQN-18690A (18-Deoxyherboxidiene)

Matsumoto, Y., Hibino, K., Yonaga, M., Kakeya, H. & Hayashi, Y., 2016 Jul 15, In : Organic letters. 18, 14, p. 3382-3385 4 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Formal Synthesis of Ezetimibe Using a Proline-mediated, Asymmetric, Three-component Mannich Reaction

Shimasaki, Y., Koshino, S. & Hayashi, Y., 2016, In : Chemistry Letters. 45, 1, p. 30-32 3 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Mechanism of Oxidative Amidation of Nitroalkanes with Oxygen and Amine Nucleophiles by Using Electrophilic Iodine

Li, J., Lear, M. J., Kwon, E. & Hayashi, Y., 2016 Apr 11, In : Chemistry - A European Journal. 22, 16, p. 5538-5542 5 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
17 Citations (Scopus)

Pot economy and one-pot synthesis

Hayashi, Y., 2016 Jan 1, In : Chemical Science. 7, 2, p. 866-880 15 p.

Research output: Contribution to journalReview article

379 Citations (Scopus)

Sterically Demanding Oxidative Amidation of α-Substituted Malononitriles with Amines Using O2

Li, J., Lear, M. J. & Hayashi, Y., 2016, In : Angewandte Chemie - International Edition. 55, 31, p. 9060-9064 5 p.

Research output: Contribution to journalArticle

24 Citations (Scopus)

The DFT calculation with NBO analysis of E/Z enamines derived from α-alkoxyaldehyde with pyrrolidine

Mukaiyama, T., Uchimaru, T. & Hayashi, Y., 2016 Jan 1, In : Bulletin of the Chemical Society of Japan. 89, 4, p. 455-459 5 p.

Research output: Contribution to journalArticle

3 Citations (Scopus)

Time Economical Total Synthesis of (-)-Oseltamivir

Hayashi, Y. & Ogasawara, S., 2016 Jul 15, In : Organic letters. 18, 14, p. 3426-3429 4 p.

Research output: Contribution to journalArticle

32 Citations (Scopus)

Total synthesis of avermectin B1a revisited

Yamashita, S., Hayashi, D., Nakano, A., Hayashi, Y. & Hirama, M., 2016 Jan 1, In : Journal of Antibiotics. 69, 1, p. 31-50 20 p.

Research output: Contribution to journalArticle

9 Citations (Scopus)

Total Synthesis of the 7,10-Epimer of the Proposed Structure of Amphidinolide N, Part I: Synthesis of the C1-C13 Subunit

Ochiai, K., Kuppusamy, S., Yasui, Y., Okano, T., Matsumoto, Y., Gupta, N. R., Takahashi, Y., Kubota, T., Kobayashi, J. & Hayashi, Y., 2016 Mar 1, In : Chemistry - A European Journal. 22, 10, p. 3282-3286 5 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Total Synthesis of the 7,10-Epimer of the Proposed Structure of Amphidinolide N, Part II: Synthesis of C17-C29 Subunit and Completion of the Synthesis

Ochiai, K., Kuppusamy, S., Yasui, Y., Harada, K., Gupta, N. R., Takahashi, Y., Kubota, T., Kobayashi, J. & Hayashi, Y., 2016 Mar 1, In : Chemistry - A European Journal. 22, 10, p. 3287-3291 5 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)
2015

Asymmetric aldol reaction of chloral catalyzed by diarylprolinol

Hayashi, Y., Watanabe, S., Yasui, Y. & Umemiya, S., 2015 Jun 1, In : ChemCatChem. 7, 11, p. 1646-1649 4 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Asymmetric Aldol Reaction of α,α-Disubstituted Acetaldehydes Catalyzed by Diphenylprolinol Silyl Ether for the Construction of Quaternary Stereogenic Centers

Hayashi, Y., Shomura, H., Xu, Q., Lear, M. J. & Sato, I., 2015 Jul 1, In : European Journal of Organic Chemistry. 2015, 20, p. 4316-4319 4 p.

Research output: Contribution to journalArticle

5 Citations (Scopus)
6 Citations (Scopus)

Asymmetric Nitrocyclopropanation of α-Substituted α,β-Enals Catalyzed by Diphenylprolinol Silyl Ether for the Construction of All-Carbon Quaternary Stereogenic Centers

Hayashi, Y., Yamazaki, T., Nakanishi, Y., Ono, T., Taniguchi, T., Monde, K. & Uchimaru, T., 2015 Sep 1, In : European Journal of Organic Chemistry. 2015, 26, p. 5747-5754 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Asymmetric organocatalyzed epoxidation of 2-oxoindoline-3-ylidene acetaldehydes

Mukaiyama, T., Ogata, K., Ono, T. & Hayashi, Y., 2015 Jan 1, In : ChemCatChem. 7, 1, p. 155-159 5 p.

Research output: Contribution to journalArticle

8 Citations (Scopus)

Oxidative Amidation of Nitroalkanes with Amine Nucleophiles using Molecular Oxygen and Iodine

Li, J., Lear, M. J., Kawamoto, Y., Umemiya, S., Wong, A. R., Kwon, E., Sato, I. & Hayashi, Y., 2015 Oct 1, In : Angewandte Chemie - International Edition. 54, 44, p. 12986-12990 5 p.

Research output: Contribution to journalArticle

37 Citations (Scopus)

Practical route to the left wing of CTX1B and total syntheses of CTX1B and 54-deoxyCTX1B

Yamashita, S., Takeuchi, K., Koyama, T., Inoue, M., Hayashi, Y. & Hirama, M., 2015 Feb 2, In : Chemistry - A European Journal. 21, 6, p. 2621-2628 8 p.

Research output: Contribution to journalArticle

6 Citations (Scopus)