Shusuke Tomoshige

Assistant Professor

  • 147 Citations
  • 7 h-Index
20132020

Research output per year

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Research Output

  • 147 Citations
  • 7 h-Index
  • 19 Article
  • 3 Review article
  • 1 Comment/debate
2020

Application of protein knockdown strategy targeting β-sheet structure to multiple disease-associated polyglutamine proteins

Yamashita, H., Tomoshige, S., Nomura, S., Ohgane, K., Hashimoto, Y. & Ishikawa, M., 2020 Jan 1, In : Bioorganic and Medicinal Chemistry. 28, 1, 115175.

Research output: Contribution to journalArticle

Open Access
4 Citations (Scopus)

Dimerizations of 2-bromo-3-methyl-1,4-naphthoquinone and 2-methyl-1,4-naphthoquinone in tetra-n-butylammonium bromide

Onuki, M., Ota, M., Otokozawa, S., Kamo, S., Tomoshige, S., Tsubaki, K. & Kuramochi, K., 2020 Feb 7, In : Tetrahedron. 76, 6, 130899.

Research output: Contribution to journalArticle

Isolation, synthesis, and biological activities of a bibenzyl from Empetrum nigrum var. Japonicum

Oka, S., Kuniba, R., Tsuboi, N., Tsuchida, S., Ushida, K., Tomoshige, S. & Kuramochi, K., 2020 Jan 1, In : Bioscience, Biotechnology and Biochemistry. 84, 1, p. 31-36 6 p.

Research output: Contribution to journalArticle

Selective degradation of target proteins by chimeric small-molecular drugs, PROTACs and SNIPERs

Ishikawa, M., Tomoshige, S., Demizu, Y. & Naito, M., 2020 Apr, In : Pharmaceuticals. 13, 4, 74.

Research output: Contribution to journalReview article

Open Access

Synthesis and structural revision of an indanone isolated from Triphyophyllum peltatum

Ishii, Y., Ota, M., Kamo, S., Tomoshige, S., Tsubaki, K. & Kuramochi, K., 2020 Feb 13, In : Tetrahedron Letters. 61, 7, 151494.

Research output: Contribution to journalArticle

Synthesis of nucleotide analogues, EFdA, EdA and EdAP, and the effect of EdAP on hepatitis B virus replication

Kamata, M., Takeuchi, T., Hayashi, E., Nishioka, K., Oshima, M., Iwamoto, M., Nishiuchi, K., Kamo, S., Tomoshige, S., Watashi, K., Kamisuki, S., Ohrui, H., Sugawara, F. & Kuramochi, K., 2020 Feb 1, In : Bioscience, Biotechnology and Biochemistry. 84, 2, p. 217-227 11 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)
2019
Open Access

Slt, MltD, and MltG of Pseudomonas aeruginosa as Targets of Bulgecin A in Potentiation of β-Lactam Antibiotics

Dik, D. A., Madukoma, C. S., Tomoshige, S., Kim, C., Lastochkin, E., Boggess, W. C., Fisher, J. F., Shrout, J. D. & Mobashery, S., 2019 Jan 1, (Accepted/In press) In : ACS Chemical Biology.

Research output: Contribution to journalArticle

6 Citations (Scopus)

Synthesis, antibacterial and cytotoxic evaluation of flavipucine and its derivatives

Kusakabe, Y., Mizutani, S., Kamo, S., Yoshimoto, T., Tomoshige, S., Kawasaki, T., Takasawa, R., Tsubaki, K. & Kuramochi, K., 2019 Jun 1, In : Bioorganic and Medicinal Chemistry Letters. 29, 11, p. 1390-1394 5 p.

Research output: Contribution to journalArticle

4 Citations (Scopus)

Synthetic and Biological Studies of Juglorubin and Related Naphthoquinones

Kamo, S., Saito, T., Kusakabe, Y., Tomoshige, S., Uchiyama, M., Tsubaki, K. & Kuramochi, K., 2019 Nov 1, In : Journal of Organic Chemistry. 84, 21, p. 13957-13966 10 p.

Research output: Contribution to journalArticle

1 Citation (Scopus)

Total Syntheses of Pyocyanin, Lavanducyanin, and Marinocyanins A and B

Kohatsu, H., Kamo, S., Tomoshige, S. & Kuramochi, K., 2019 Sep 20, In : Organic letters. 21, 18, p. 7311-7314 4 p.

Research output: Contribution to journalArticle

Unified Approach toward Syntheses of Juglomycins and Their Derivatives

Yoshioka, K., Kamo, S., Hosaka, K., Sato, R., Miikeda, Y., Manabe, Y., Tomoshige, S., Tsubaki, K. & Kuramochi, K., 2019 Jul 31, In : ACS Omega. 4, 7, p. 11737-11748 12 p.

Research output: Contribution to journalArticle

Open Access
2018

Degradation of huntingtin mediated by a hybrid molecule composed of IAP antagonist linked to phenyldiazenyl benzothiazole derivative

Tomoshige, S., Nomura, S., Ohgane, K., Hashimoto, Y. & Ishikawa, M., 2018 Feb 15, In : Bioorganic and Medicinal Chemistry Letters. 28, 4, p. 707-710 4 p.

Research output: Contribution to journalArticle

7 Citations (Scopus)

Exolytic and endolytic turnover of peptidoglycan by lytic transglycosylase Slt of Pseudomonas aeruginosa

Lee, M., Batuecas, M. T., Tomoshige, S., Domínguez-Gil, T., Mahasenan, K. V., Dik, D. A., Hesek, D., Millán, C., Usón, I., Lastochkin, E., Hermoso, J. A. & Mobashery, S., 2018 Apr 24, In : Proceedings of the National Academy of Sciences of the United States of America. 115, 17, p. 4393-4398 6 p.

Research output: Contribution to journalArticle

Open Access
9 Citations (Scopus)

Total Syntheses of Bulgecins A, B, and C and Their Bactericidal Potentiation of the β-Lactam Antibiotics

Tomoshige, S., Dik, D. A., Akabane-Nakata, M., Madukoma, C. S., Fisher, J. F., Shrout, J. D. & Mobashery, S., 2018 Jun 8, In : ACS Infectious Diseases. 4, 6, p. 860-867 8 p.

Research output: Contribution to journalArticle

Open Access
8 Citations (Scopus)
2017

Discovery of Small Molecules that Induce the Degradation of Huntingtin

Tomoshige, S., Nomura, S., Ohgane, K., Hashimoto, Y. & Ishikawa, M., 2017 Jan 1, In : Angewandte Chemie - International Edition. 56, 38, p. 11530-11533 4 p.

Research output: Contribution to journalArticle

22 Citations (Scopus)
2016

Cover Picture: Improvement in Aqueous Solubility of Retinoic Acid Receptor (RAR) Agonists by Bending the Molecular Structure (Chem. Asian J. 15/2016)

Hiramatsu, M., Ichikawa, Y., Tomoshige, S., Makishima, M., Muranaka, A., Uchiyama, M., Yamaguchi, T., Hashimoto, Y. & Ishikawa, M., 2016 Aug 5, In : Chemistry - An Asian Journal. 11, 15, 1 p.

Research output: Contribution to journalComment/debate

16 Citations (Scopus)

Improvement in Aqueous Solubility of Retinoic Acid Receptor (RAR) Agonists by Bending the Molecular Structure

Hiramatsu, M., Ichikawa, Y., Tomoshige, S., Makishima, M., Muranaka, A., Uchiyama, M., Yamaguchi, T., Hashimoto, Y. & Ishikawa, M., 2016 Aug 5, In : Chemistry - An Asian Journal. 11, 15, p. 2210-2217 8 p.

Research output: Contribution to journalArticle

2 Citations (Scopus)
2015

Degradation of HaloTag-fused nuclear proteins using bestatin-HaloTag ligand hybrid molecules

Tomoshige, S., Naito, M., Hashimoto, Y. & Ishikawa, M., 2015 Aug 24, In : Organic and Biomolecular Chemistry. 13, 38, p. 9746-9750 5 p.

Research output: Contribution to journalArticle

31 Citations (Scopus)
2013

Structure-activity relationships of bisphenol a analogs at estrogen receptors (ERs): Discovery of an ERα-selective antagonist

Maruyama, K., Nakamura, M., Tomoshige, S., Sugita, K., Makishima, M., Hashimoto, Y. & Ishikawa, M., 2013 Jul 15, In : Bioorganic and Medicinal Chemistry Letters. 23, 14, p. 4031-4036 6 p.

Research output: Contribution to journalArticle

36 Citations (Scopus)